Phase evolution

Evolution of amphiphilic phases

Widom evolution

The model shows that combinatorial amphiphile systems can indeed evolve to control their collective phase, in order to promote their proliferation and survival.


This is a non-trivial result, given the general difficulty of cooperation (group selection) in evolving molecular systems.


There is currently no selective advantage in the model for forming a vesicular phase, but this example shows how weak combinatorial amphiphiles can evolve to increase the amount of interface in a system.


A similar calculation in a still simpler model of an Ising fluid also demonstrated that cooperative phase control can be evolved effectively in physical systems.


These models provide insight into the range of options for self-assembling artificial cells and their potential to evolve to stable systems. For details, please consult the original article.